Which medication category does not directly impact blood glucose levels?

Statins belong to a class of medications primarily used to lower cholesterol levels and manage cardiovascular disease risk. They work by inhibiting an enzyme involved in cholesterol production in the liver. While there is some evidence suggesting that statins may influence insulin sensitivity indirectly, they do not have a direct mechanism for lowering or raising blood glucose levels like other medication categories do.

In contrast, biguanides (such as Metformin) primarily work to decrease hepatic glucose production and improve insulin sensitivity, directly impacting blood glucose levels. Insulin derivatives are designed to replace or supplement the insulin that the body produces, thereby directly lowering blood glucose levels. Finally, alpha-glucosidase inhibitors work by delaying carbohydrate absorption in the intestine, which impacts postprandial blood glucose levels directly. Given their mechanisms of action, it’s clear that statins do not have a direct effect on blood glucose regulation, making them the category that does not impact blood glucose levels in the same way as the other medications listed.